10 years after the last book, Potterheads are still incredibly protective of their literary couples, and it's kind of awesome that this fandom has remained so passionate and loyal for so long.
That said, I also think that the interview isn't that big of a deal.
Don't get me wrong, I was heartbroken when I first heard the news. How could Hermione and Ron, everyone's favorite book nerd and ginger (respectively), end up with anyone else? Does this mean that everything- the fourth year drama, Ron's showdown with the Horcrux in year seven- is a lie????
Because the Harry Potter books are over, and there's no way to change what happened in them. Regardless of how our beloved J.K. Rowling feels so many years later, the story is finished and Ron and Hermione did end up together. Whether that is a good pairing or not doesn't change that fact (though, I will say that Hermione and Ron balance each other out, which is why I believe their relationship would work).
Once Deathly Hallows made it into the hands of us, the readers, the ending was the ending, plain and simple. And as John Green put it, "Books belong to their readers." So I'm not going to get all bothered over this interview- J.K. Rowling has the right to say what she wants concerning the books she wrote, just like we have the right to adore Hermione and Ron.
And besides, were the books ever really about romance anyway?